Novel stimulants sold as MDMA, cocaine or speed

There have been a number of recent emergency department presentations linked to these substances in Victoria, particularly in the Melbourne and Bendigo areas.

Both synthetic cathinones and PMMA can produce similar effects to common stimulants such as methamphetamine, cocaine or MDMA but appear to have a higher risk of producing negative effects. People who have used synthetic cathinones report that they produce less euphoria and psychedelic effects compared with taking MDMA, and that these effects wear off more quickly. This can lead to people taking more (re-dosing), increasing the risk of toxicity.

At higher doses, synthetic cathinones can lead to long periods of sleeplessness and muscle twitching, increased risk of agitation, paranoia and hallucinations, and toxic effects such as overheating and heart problems.

PMMA has been responsible for several overdose deaths in Australia since the 1990s. Depending on the amount taken, it seems to have a significant risk of very serious harm to health. This includes hyperthermia (dangerously high body temperature), convulsions, sudden collapse, multiple organ failure, cardiac arrest and death. Be very cautious if you have recently purchased a black or grey powder sold as MDMA in Victoria – it may contain PMMA.

Some common mental health medications – such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs) and trycyclic antidepressants (TCAs) – may increase the risk of toxicity from stimulants. Always seek information about your medications before mixing with other substances.

If you experience adverse drug effects, or are present when someone has an unexpected reaction, seek help immediately by calling Triple Zero (000).

All alcohol and other drug use comes with risks, so:

Contact Harm Reduction Victoria’s DanceWize team for anonymous support and education from peers. Talk to DanceWize volunteers by email at [email protected] or call (03) 9329 1500 (Mon-Thurs, 10am-6pm)

If you or someone you know needs help with alcohol or drug use, call DirectLine on 1800 888 236 or visit DirectlineExternal Link for information and support to access treatment.

Reviewed 05 May 2023